All data in Rhea is freely accessible and available for download from our FTP sites:


Reactions are available in several data formats:

Relations between reactions (e.g. reaction_A is a reaction_B) are available as a tab-separated values file: rhea-relationships.tsv

Reaction participants

Information about the chemical entities that participate in Rhea reactions is available in the following files:


Rhea cross-references to other databases are available as tab-separated values files:

All Rhea tsv files can be downloaded in a single archive: rhea-tsv.tar.gz